During the many years of work at our center , we have observed that most forms of asthma or recurring inflammatory bronchial pathologies include a component of hypersensitive reactivity to perennial allergens. In addition to the obvious reaction to mites, there is also an ever increasing hypersensitivity to molds and fungi.
As Brandt already observed in his studies, this means that fungi can cause problems not only because of their concentration in the air, but most of all when the intestine (which represents the largest reservoir of fungi and molds) is full of them.
A study published on the first of January in the American Journal of Respiratory and Critical Care Medicine (Denning DW et al, Am J Respir Crit Care Med. 2009 Jan 1;179(1):11-8. Epub 2008 Oct 2) indicated that in many forms of severe asthma where there is a sensitization to fungi, those very fungi are in some way responsible for the exasperation of the asthma.
These patients who suffer from SAFS (Severe Asthma with Fungal Sensitization) with a reactivity to one or more fungi, although not to precipitine all’aspergillus (a particular type of reactivity typical of allergic aspergillosis) and whose IgE’s are less than 1000 Ul/mL (a frequent situation among our patients) show a clear and significant improvement in their asthma thanks to antifungal treatment.
In the study this treatment was extended for 32 weeks at high dosages (200 mgs twice daily) and resulted in a 60% rate of improvement demonstrated by the morning expiratory peak, reduction in rhinitis and most of all in the patients’ enhanced perception of well-being.
This is not the type of treatment that we would normally prescribe to a patient since we prefer less toxic medicines such as metronidazole (Flagyl) or shorter periods of treatment, accompanied by natural cures (Melaleuca and a control diet for yeasts, for example)
The problem that arises from this scientific work, which is extremely interesting and backed by the producers of itraconazole (Sporanox, Janssen and Triasporin Italfarmaco) and of the similar product Flucnasole (Diflucan), is the possibility of major side effects connected with a such a prolonged treatment. The study exploited the long-term use of the drug.
However, we know that in addition to the use of these drugs, the restoration of the intestine’s ability to regulate fungi, the use of an oral hyposensitizer for the specific fungus (Aspergillus, Penicillium, Candida, etc.) and the use of mineral (for example Oximix 1+) or vegetable (Fitocurcuma) compositions that stimulate the immune system. Of course Melaleuca (Tea-tree oil) is always an effective therapeutic aid.
Thus, dietary cleansing is one of the most important options available to us for reducing the irritation caused by yeasts and restoring vitality in a way that one might not have thought possible.